The GenoQuantTM Periodontal Bacteria qPCR Assay is designed for qualitative and quantitative analysis of six common periodontal bacteria in human saliva.
Periodontitis is a highly prevalent chronic inflammatory disease leading to the loss of periodontal tissues, which is the major cause of tooth loss in adults. Several periodontal bacteria have been identified to be responsible for the disease and may relevant to other systemic infectious diseases including meningitis, osteomyelitis, and arthritis. Each group of bacteria plays a significant different role in the pathogenesis of periodontitis.
This assay provides not only direct evidence on the presence of microbes, but also the bacteria count (copies/μL) of six common periodontal bacteria (Aggregatibacter actinomycetemcomitans (AA), Porphyromonas gingivalis (PG), Tannerella forsythensis (TF), Treponema denticola (TD), Prevotella intermedia (PI), and Fusobacterium nucleatum (FN)).
This assay is intended exclusively for in vitro diagnostic use with the appropriate clinical laboratory settings, safety standards and properly trained personnel.
The information provided by the test is extremely valuable for practitioners to select the appropriate antibiotics in periodontitis treatment. With the provided therapeutic threshold for each bacterium, dental healthcare professionals can provide personalized antibiotics treatment to the patient and evaluate the effectiveness of treatment.
This is a consumable assay kit, developed, supplied and supported by DiagCor. It requires a compatible instrument and a meticulous MDx workflow.
Genesis 96Q Real-Time PCR System is a compact 96-well real-time PCR (qPCR) instrument with up to 6 detection channels to satisfy various analysis methods.
Catalogue number | 92030 |
Configuration | 24 tests (real time PCR assay) |
Detected genes | hbpA gene of AA; rpoB gene of PI; hsp60 gene of TF; cfpA gene of TD; fadA gene of FN; rpoB gene of PG; RPP gene of AC |
Specimens | Human saliva |
Internal controls | PS1, PS2, NC, AC |
Reported results | AA/PI/TF/TD/FN/PG/AC positive/negative & therapeutic threshold |