Tissue biopsy / Abortus tissue / Product of conception

CAB

Small sample (1 cu. cm) of placental / fetal tissue

Sterile container with sterile Ringer's lactate or Hanks' balanced salt solution. Urine container is not suitable

Nil

Obtain a small piece of tissue with subepidermal layers aseptically. Tissue from placental villi most preferred, as it remains viable longer than fetal tissue. This is especially true in stillborn cases in which both cord blood and tissue samples are often not viable

Necrotic tissue; Gross contamination; specimen in fixative

Nil

Tissue culture following enzymatic digestion of tissue. Standard harvesting and G-banding procedures are used with 20 metaphases examined and two karyotypes prepared

Some specimen of conception may only contain maternal tissue

Specimen should be kept at room temperature

International System for Human Cytogenetic Nomenclature (2009)